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Merck

KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

別名:
ERD2L3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(11015) Summary: This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Mouse(105785) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • Rat(315131) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • chicken(418026) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • naked mole-rat(101706113) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • Zebrafish(393613) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • domestic guinea pig(100727776) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • domestic cat(101080390) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • cow(509687) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • dog(474509) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗KDELR3抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗KDELR3抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human KDELR3,
Species
human
MISSION® esiRNA, targeting mouse Kdelr3,
Species
mouse