コンテンツへスキップ
Merck

KCNN2

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

別名:
KCa2.2, SK2, SKCA2, SKCa 2, hSK2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3781) Summary: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
  • Mouse(140492) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • Rat(54262) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • naked mole-rat(101725711) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • domestic guinea pig(100734732) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • sheep(101105660) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • domestic cat(101099926) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • cow(404177) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • dog(474640) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
  • chicken(395579) potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SK2 (KCa2.2) Antibody, clone K78/29, clone K78/29, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Potassium Channel SK2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
交差性
human, rat
アプリケーション
western blot
抗KCNN2抗体 ウサギ宿主抗体, IgG fraction of antiserum,
交差性
human, yeast
アプリケーション
immunohistochemistry
western blot
抗KCNN2抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Kcnn2,
Species
mouse
MISSION® esiRNA, targeting human KCNN2,
Species
human