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Merck

IDO1

indoleamine 2,3-dioxygenase 1

別名:
IDO, IDO-1, INDO
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3620) Summary: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
  • Mouse(15930) indoleamine 2,3-dioxygenase 1
  • Rat(66029) indoleamine 2,3-dioxygenase 1
  • Zebrafish(571967) indoleamine 2,3-dioxygenase 1
  • dog(475574) indoleamine 2,3-dioxygenase 1
  • domestic guinea pig(100728309) indoleamine 2,3-dioxygenase 1
  • naked mole-rat(101723745) indoleamine 2,3-dioxygenase 1
  • domestic cat(101096977) indoleamine 2,3-dioxygenase 1
  • cow(506281) indoleamine 2,3-dioxygenase 1
  • sheep(100196903) indoleamine 2,3-dioxygenase 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗IDO1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
抗IDO1抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-IDO-1 Antibody, clone 4B7 | MABF850, clone 4B7, from mouse,
交差性
mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Indoleamine 2,3-dioxygenase Antibody, clone 10.1, clone 10.1, Chemicon®, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-Ido1, clone 8G11 Antibody, clone 8G11, from mouse,
交差性
mouse
アプリケーション
flow cytometry
western blot

Proteins

製品番号
詳細
Species
Mouse IDO1, His-Tag, recombinant, expressed in E. coli,
Species
mouse