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Merck

IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

別名:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
  • Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
  • Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗IDH2抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, canine, human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry

western blot
抗IDH2抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
Anti-IDH2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

Kits

製品番号
詳細
Species
IDH Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
mouse, rat, human

Proteins

製品番号
詳細
Species
IDH2, FLAG® -Tag, recombinant, expressed in baculovirus infected Sf9 cells,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human IDH2,
Species
human
MISSION® esiRNA, targeting mouse Idh2,
Species
mouse