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HUS1

HUS1 checkpoint homolog (S. pombe)

別名:
hHUS1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3364) Summary: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
  • Mouse(15574) Hus1 homolog (S. pombe)
  • Rat(498411) HUS1 checkpoint homolog (S. pombe)
  • sheep(101113059) HUS1 checkpoint homolog (S. pombe)
  • dog(606789) HUS1 checkpoint homolog (S. pombe)
  • domestic cat(101081456) HUS1 checkpoint homolog (S. pombe)
  • Horse(100066083) HUS1 checkpoint homolog (S. pombe)
  • naked mole-rat(101704977) HUS1 checkpoint homolog (S. pombe)
  • domestic guinea pig(100713541) HUS1 checkpoint homolog (S. pombe)
  • chicken(428471) HUS1 checkpoint homolog (S. pombe)
  • cow(514142) HUS1 checkpoint homolog (S. pombe)

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-HUS1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-HUS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-HUS1 antibody produced in mouse, clone 2B12, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)
Anti-HUS1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human HUS1 (2),
Species
human
MISSION® esiRNA, targeting mouse Hus1,
Species
mouse
MISSION® esiRNA, targeting human HUS1,
Species
human