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Merck

HMGCL

3-hydroxymethyl-3-methylglutaryl-CoA lyase

別名:
HL
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3155) Summary: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(15356) 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
  • Rat(79238) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • Zebrafish(394190) 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)
  • naked mole-rat(101716848) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • domestic guinea pig(100713291) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • domestic cat(101099569) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • cow(317658) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • chicken(396316) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • dog(478187) 3-hydroxymethyl-3-methylglutaryl-CoA lyase
  • sheep(101119699) 3-hydroxymethyl-3-methylglutaryl-CoA lyase

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗HMGCL抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
抗HMGCL抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
メバスタチン, ≥98% (HPLC), powder or crystals,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Hmgcl,
Species
mouse