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Merck

GP1BA

glycoprotein Ib (platelet), alpha polypeptide

別名:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
  • Mouse(14723) glycoprotein 1b, alpha polypeptide
  • Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
  • chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
  • naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
  • domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
  • sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
  • cow(504977) glycoprotein Ib (platelet), alpha polypeptide
  • domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
  • dog(403638) glycoprotein Ib (platelet), alpha polypeptide

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Human CD42b ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
交差性
human, nonhuman primates
アプリケーション
flow cytometry
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
交差性
human
アプリケーション
flow cytometry
Anti-CD42b/GP1BA Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
affinity binding assay
immunocytochemistry

western blot
Anti-GP1BA antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GP1BA,
Species
human
MISSION® esiRNA, targeting mouse Gp1ba,
Species
mouse