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Merck

FCN3

ficolin (collagen/fibrinogen domain containing) 3

別名:
FCNH, HAKA1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8547) Summary: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq, Jul 2008]
  • naked mole-rat(101698364) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • cow(782648) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • sheep(101113473) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • domestic cat(101082073) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • domestic guinea pig(100736025) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • Horse(100070924) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
  • dog(100685339) ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

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ELISA

製品番号
詳細
Species
Human Ficolin-3 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-FCN3 antibody produced in mouse, clone 4B4, ascites fluid,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human FCN3,
Species
human