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Merck

F11

coagulation factor XI

別名:
FXI
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2160) Summary: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
  • Mouse(109821) coagulation factor XI
  • Rat(290757) coagulation factor XI
  • chicken(422723) coagulation factor XI
  • naked mole-rat(101717554) coagulation factor XI
  • domestic guinea pig(100715511) coagulation factor XI
  • Domestic Rabbit(100009596) coagulation factor XI
  • sheep(101116630) coagulation factor XI
  • cow(407998) coagulation factor XI
  • Horse(100056603) coagulation factor XI
  • domestic cat(101094340) coagulation factor XI
  • domestic cat(493756) coagulation factor XI
  • dog(475623) coagulation factor XI

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ELISA

製品番号
詳細
Species
Human Coagulation Factor XI ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-F11 antibody produced in mouse, clone 3C7, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
Anti-F11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-F11 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human F11,
Species
human