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Merck

EDN3

endothelin 3

別名:
ET-3, ET3, HSCR4, PPET3, WS4B
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1908) Summary: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(13616) endothelin 3
  • Rat(366270) endothelin 3
  • cow(513753) endothelin 3
  • naked mole-rat(101722729) endothelin 3
  • dog(403406) endothelin 3
  • chicken(768509) endothelin 3
  • Horse(100034064) endothelin 3
  • sheep(101114458) endothelin 3
  • domestic guinea pig(100733839) endothelin 3

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-EDN3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-EDN3 Mouse mAb (2A6-2A4), liquid, clone 2A6-2A4, Calbiochem®,
交差性
human
アプリケーション

Proteins

製品番号
詳細
Species
ヒト、ラットエンドセリン3, ≥97% (HPLC), powder,
Species
human, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Edn3,
Species
mouse
MISSION® esiRNA, targeting human EDN3,
Species
human