コンテンツへスキップ
Merck

DUX4

double homeobox 4

別名:
DUX10
Species:
UniProtKB ID:
遺伝子ID:
  • Human(22947) Summary: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. There is no evidence for transcription of this gene from standard cDNA libraries, however, RT-PCR and in vitro expression experiments indicate that the ORF is transcribed. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq, May 2013]
  • dog(491532) uncharacterized LOC491532

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
抗Dux4抗体、クローン9A12, clone 9A12, from mouse,
交差性
human
アプリケーション
electrophoretic mobility shift assay
immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-DUX4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-DUX4 antibody produced in mouse, clone P2B1, 1 mg/mL, purified immunoglobulin,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-DUX4 Antibody, clone P4H2, clone P4H2, from mouse,
交差性
human
アプリケーション
immunocytochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human DUX4,
Species
human