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Merck

DHCR24

24-dehydrocholesterol reductase

別名:
DCE, Nbla03646, SELADIN1, seladin-1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1718) Summary: This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008]
  • Mouse(74754) 24-dehydrocholesterol reductase
  • Rat(298298) 24-dehydrocholesterol reductase
  • domestic guinea pig(100714000) 24-dehydrocholesterol reductase
  • naked mole-rat(101703975) 24-dehydrocholesterol reductase
  • dog(489573) 24-dehydrocholesterol reductase
  • domestic cat(101098730) 24-dehydrocholesterol reductase
  • Horse(100034055) 24-dehydrocholesterol reductase
  • cow(533726) 24-dehydrocholesterol reductase
  • sheep(101123162) 24-dehydrocholesterol reductase
  • Zebrafish(494102) 24-dehydrocholesterol reductase
  • chicken(424661) 24-dehydrocholesterol reductase

Custom & Knockdown Gene Products

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗DHCR24 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-DHCR24 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
抗DHCR24抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗DHCR24抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, human, mouse, rabbit, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
トリパラノール, ≥97% (HPLC), powder,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Dhcr24,
Species
mouse
MISSION® esiRNA, targeting human DHCR24,
Species
human