DCC
deleted in colorectal carcinoma
別名:
CRC18, CRCR1, IGDCC1, MRMV1
Species:
Human DCC (1630), Mouse Dcc (13176), Rat Dcc (25311), Zebrafish dcc (569360), dog DCC (483976), domestic cat DCC (101098832), Horse DCC (100054013), cow DCC (537176), sheep DCC (101118654), domestic guinea pig Dcc (100712666)
UniProtKB ID:
遺伝子ID:
- Human(1630) Summary: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
- Mouse(13176) deleted in colorectal carcinoma
- Rat(25311) deleted in colorectal carcinoma
- Zebrafish(569360) deleted in colorectal carcinoma
- dog(483976) deleted in colorectal carcinoma
- domestic cat(101098832) deleted in colorectal carcinoma
- Horse(100054013) deleted in colorectal carcinoma
- cow(537176) deleted in colorectal carcinoma
- sheep(101118654) deleted in colorectal carcinoma
- domestic guinea pig(100712666) deleted in colorectal carcinoma
- naked mole-rat(101705571) deleted in colorectal carcinoma
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗DCC抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗DCC抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗DCC ウサギ宿主抗体, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunofluorescence
Anti-phospho DCC (Tyr1418), serum, from rabbit,
交差性
rat
アプリケーション
dot blot
immunofluorescence
western blot
immunofluorescence
western blot
抗DCC抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
esiRNA
製品番号
詳細
Species