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Merck

CKMT1B

creatine kinase, mitochondrial 1B

別名:
CKMT, CKMT1, UMTCK
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1159) Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
  • Rat(29593) creatine kinase, mitochondrial 1B
  • dog(478277) creatine kinase, mitochondrial 1B
  • domestic cat(101097983) creatine kinase, mitochondrial 1B
  • Horse(100056283) creatine kinase, mitochondrial 1B
  • naked mole-rat(101725224) creatine kinase, mitochondrial 1B
  • sheep(101108520) creatine kinase, mitochondrial 1B
  • cow(281692) creatine kinase, mitochondrial 1B

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
モノクローナル抗CKMT1B抗体 マウス宿主抗体, clone 2C8, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Monoclonal Anti-CKMT1B, (C-terminal) antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot