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Merck

CILP

cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

別名:
CILP-1, HsT18872
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8483) Summary: Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
  • Mouse(214425) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Rat(315761) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Zebrafish(553329) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • cow(100336614) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • Horse(100053337) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic cat(101084795) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • dog(487603) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • sheep(101119218) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • chicken(415533) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • naked mole-rat(101723750) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
  • domestic guinea pig(100721580) cartilage intermediate layer protein, nucleotide pyrophosphohydrolase

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ELISA

製品番号
詳細
Species
Human CILP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-CILP antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
抗CILP抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Cilp,
Species
mouse
MISSION® esiRNA, targeting human CILP,
Species
human