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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

別名:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
UniProtKB ID:
遺伝子ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

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ELISA

製品番号
詳細
Species
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
交差性
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, serum, Upstate®,
交差性
human
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat, clone DECMA-1, purified from hybridoma cell culture,
交差性
dog, mouse
アプリケーション
immunofluorescence
immunoprecipitation (IP)

western blot
Monoclonal Anti-CDH1 antibody produced in mouse, clone 3F4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry

proximity ligation assay

western blot

Cell Lines

製品番号
詳細
Species
MCF10A 細胞 CDH1 (-/-), ,
Species
human

Proteins

製品番号
詳細
Species
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Species
human
E-カドヘリン/Fcキメラ マウス由来, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Cdh1,
Species
mouse
MISSION® esiRNA, targeting human CDH1,
Species
human