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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

別名:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Species:
UniProtKB ID:
遺伝子ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-E-Cadherin Antibody, serum, Upstate®,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-E-cadherin antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-E-Cadherin antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-E-Cadherin Antibody, clone 67A4, Azide Free, clone 67A4, Chemicon®, from mouse,
交差性
human
アプリケーション
flow cytometry
immunofluorescence
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
交差性
canine, human
アプリケーション
ELISA
immunocytochemistry

inhibition assay

western blot

Cell Lines

製品番号
詳細
Species
MCF10A 細胞 CDH1 (-/-), ,
Species
human

Proteins

製品番号
詳細
Species
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Species
human
E-カドヘリン/Fcキメラ マウス由来, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
mouse

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CDH1,
Species
human
MISSION® esiRNA, targeting mouse Cdh1,
Species
mouse