CASP5
caspase 5, apoptosis-related cysteine peptidase
別名:
ICE(rel)III, ICEREL-III, ICH-3
Species:
UniProtKB ID:
遺伝子ID:
- Human(838) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti Caspase 5 Antibody, clone 23GB3315, Rabbit Monoclonal, clone 23GB3315, recombinant rabbit monoclonal, expressed in HEK293 cells,
交差性
human, rat
アプリケーション
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CASP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-Caspase-5 Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
immunocytochemistry
immunofluorescence
western blot
immunofluorescence
western blot
Proteins
製品番号
詳細
Species
esiRNA
製品番号
詳細
Species