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Merck

CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

別名:
CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, SANDD
Species:
UniProtKB ID:
遺伝子ID:
  • Human(776) Summary: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(12289) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Rat(29716) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • sheep(101106371) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic cat(101088394) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Domestic Rabbit(100327259) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • chicken(395895) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Horse(100051186) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • dog(484724) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic guinea pig(100726255) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • cow(408013) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • naked mole-rat(101714832) calcium channel, voltage-dependent, L type, alpha 1D subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
ガバペンチン, United States Pharmacopeia (USP) Reference Standard,
Species
human
ガバペンチン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
ガバペンチン 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
プレガバリン, European Pharmacopoeia (EP) Reference Standard,
Species
human
ガバペンチン 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
ニモジピン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
ニモジピン, United States Pharmacopeia (USP) Reference Standard,
Species
human
シンナリジン, European Pharmacopoeia (EP) Reference Standard,
Species
human
フェロジピン, United States Pharmacopeia (USP) Reference Standard,
Species
human
フェロジピン, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CACNA1D antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-CACNA1D antibody produced in mouse, clone S48A-9, 1 mg/mL, purified immunoglobulin,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)

western blot
抗カルシウムチャネル(α1Dサブユニット) (L型電位依存性Ca2+チャネル)抗体 ウサギ宿主抗体, affinity isolated antibody, lyophilized powder,
交差性
mouse, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

製品番号
詳細
Species
Margatoxin, ,
Species
mouse, rat, human
ベジル酸アムロジピン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
ベジル酸アムロジピン, ≥98% (HPLC),
Species
human
ベジル酸アムロジピン, United States Pharmacopeia (USP) Reference Standard,
Species
human
ベラパミル 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CACNA1D,
Species
human