C5AR2
complement component 5a receptor 2
別名:
C5L2, GPF77, GPR77
Species:
Human C5AR2 (27202), Mouse C5ar2 (319430), Rat C5ar2 (445269), domestic guinea pig C5ar2 (100728778), naked mole-rat C5ar2 (101712956)
UniProtKB ID:
遺伝子ID:
- Human(27202) Summary: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
- Mouse(319430) complement component 5a receptor 2
- Rat(445269) complement component 5a receptor 2
- domestic guinea pig(100728778) complement component 5a receptor 2
- naked mole-rat(101712956) complement component 5a receptor 2
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