BAG4
BCL2-associated athanogene 4
別名:
BAG-4, SODD
Species:
Human BAG4 (9530), Mouse Bag4 (67384), Rat Bag4 (361167), domestic cat BAG4 (101087659), dog BAG4 (607954), chicken BAG4 (426776), Zebrafish bag4 (100001980), Thale Cress BAG4 (824341), domestic guinea pig Bag4 (100731898), naked mole-rat Bag4 (101707505) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(9530) Summary: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
- Mouse(67384) BCL2-associated athanogene 4
- Rat(361167) BCL2-associated athanogene 4
- domestic cat(101087659) BCL2-associated athanogene 4
- dog(607954) BCL2-associated athanogene 4
- chicken(426776) BCL2-associated athanogene 4
- Zebrafish(100001980) BCL2-associated athanogene 4
- Thale Cress(824341) BCL-2-associated athanogene 4
- domestic guinea pig(100731898) BCL2-associated athanogene 4
- naked mole-rat(101707505) BCL2-associated athanogene 4
- sheep(101118503) BCL2-associated athanogene 4
- Horse(100057730) BCL2-associated athanogene 4
- cow(516353) BCL2-associated athanogene 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
製品番号
詳細
交差性
アプリケーション
抗BAG4抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗BAG4抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
抗BAG4抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot
抗SODD抗体 ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-BAG4 antibody produced in mouse, clone 2G9, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
western blot