コンテンツへスキップ
Merck

ASCC1

activating signal cointegrator 1 complex subunit 1

別名:
ASC1p50, p50
Species:
UniProtKB ID:
遺伝子ID:
  • Human(51008) Summary: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(69090) activating signal cointegrator 1 complex subunit 1
  • Rat(294512) activating signal cointegrator 1 complex subunit 1
  • Zebrafish(550273) activating signal cointegrator 1 complex subunit 1
  • chicken(423709) activating signal cointegrator 1 complex subunit 1
  • cow(534915) activating signal cointegrator 1 complex subunit 1
  • naked mole-rat(101726495) activating signal cointegrator 1 complex subunit 1
  • domestic cat(101081081) activating signal cointegrator 1 complex subunit 1
  • dog(608331) activating signal cointegrator 1 complex subunit 1
  • sheep(101113387) activating signal cointegrator 1 complex subunit 1
  • Goat(100861081) activating signal cointegrator 1 complex subunit 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
抗ASCC1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
抗ASCC1抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Ascc1,
Species
mouse
MISSION® esiRNA, targeting human ASCC1,
Species
human