AKR1C3
aldo-keto reductase family 1, member C3
別名:
DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS
Species:
Human AKR1C3 (8644), Rat Akr1c3 (171516), dog AKR1C3 (497070), cow AKR1C3 (617917), cow AKR1C3 (782884), domestic cat AKR1C3 (100510801)
UniProtKB ID:
遺伝子ID:
- Human(8644) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- Rat(171516) aldo-keto reductase family 1, member C3
- dog(497070) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
- cow(617917) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
- cow(782884) aldo-keto reductase family 1, member C1
- domestic cat(100510801) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗AKR1C3抗体, マウスモノクロナール, clone NP6.G6.A6, purified from hybridoma cell culture,
交差性
human
アプリケーション
ELISA
immunohistochemistry
microarray
western blot
immunohistochemistry
microarray
western blot
Anti-AKR1C3 Antibody, clone 7T10F5, Rabbit Monoclonal, ,
交差性
mouse
アプリケーション
immunofluorescence
western blot
western blot
Anti-AKR1C3 Antibody, clone 1I9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Proteins
製品番号
詳細
Species
Prostaglandin F Synthase human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human
esiRNA
製品番号
詳細
Species