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Merck

ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

別名:
ADAMTS-2, ADAMTS-4, ADMP-1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9507) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008]
  • Mouse(240913) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
  • Rat(66015) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • domestic cat(101089488) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • Horse(100033914) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • dog(488651) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • sheep(101106565) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • cow(286806) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • naked mole-rat(101702362) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • domestic guinea pig(100712995) ADAM metallopeptidase with thrombospondin type 1 motif, 4

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ELISA

製品番号
詳細
Species
Human ADAMTS4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-ADAMTS4, affinity isolated antibody,
交差性
bovine, guinea pig, horse, human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-ADAMTS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-ADAMTS4 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)
Anti-ADAMTS4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-ADAMTS4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

Proteins

製品番号
詳細
Species
ADAMTS-4, recombinant, His Tagged, This His Tagged Recombinant ADAMTS4 is used to study the degradation of extracellular matrix proteoglycans, to screen for inhibitors of proteoglycan hydrolysis and to characterize inhibitor actions.,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human ADAMTS4,
Species
human
MISSION® esiRNA, targeting mouse Adamts4,
Species
mouse