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Merck

ACVR1

activin A receptor, type I

別名:
ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species:
UniProtKB ID:
遺伝子ID:
  • Human(90) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
  • Mouse(11477) activin A receptor, type 1
  • Rat(79558) activin A receptor, type I
  • domestic guinea pig(100724428) activin A receptor, type I
  • naked mole-rat(101711343) activin A receptor, type I
  • chicken(395246) activin A receptor, type I
  • dog(478757) activin A receptor, type I
  • domestic cat(101091298) activin A receptor, type I
  • Horse(100050899) activin A receptor, type I
  • cow(338068) activin A receptor, type I
  • sheep(443161) activin A receptor, type I

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ELISA

製品番号
詳細
Species
Human Activin R1A ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot
Anti-ACVR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗ACVR1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-ACVR1 antibody produced in mouse, clone 2D5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
抗ACVR1抗体, affinity isolated antibody,
交差性
bovine, goat, guinea pig, horse, human, mouse
アプリケーション
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
ALK2, active, ,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Acvr1,
Species
mouse
MISSION® esiRNA, targeting human ACVR1,
Species
human