ACVR1
activin A receptor, type I
ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Human ACVR1 (90), Mouse Acvr1 (11477), Rat Acvr1 (79558), domestic guinea pig Acvr1 (100724428), naked mole-rat Acvr1 (101711343), chicken ACVR1 (395246), dog ACVR1 (478757), domestic cat ACVR1 (101091298), Horse ACVR1 (100050899), cow ACVR1 (338068)
- Human(90) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
- Mouse(11477) activin A receptor, type 1
- Rat(79558) activin A receptor, type I
- domestic guinea pig(100724428) activin A receptor, type I
- naked mole-rat(101711343) activin A receptor, type I
- chicken(395246) activin A receptor, type I
- dog(478757) activin A receptor, type I
- domestic cat(101091298) activin A receptor, type I
- Horse(100050899) activin A receptor, type I
- cow(338068) activin A receptor, type I
- sheep(443161) activin A receptor, type I
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ELISA
Antibodies
ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
human, mouse
immunohistochemistry
western blot
western blot
Anti-ACVR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
human
immunofluorescence
抗ACVR1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
Monoclonal Anti-ACVR1 antibody produced in mouse, clone 2D5, purified immunoglobulin, buffered aqueous solution,
human
ELISA
western blot
western blot
抗ACVR1抗体, affinity isolated antibody,
bovine, goat, guinea pig, horse, human, mouse
immunohistochemistry
western blot
western blot