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Safety Information

V900343

Sigma-Aldrich

L-Arginine

≥98%, Vetec™

Synonym(s):

(S)-2-Amino-5-guanidinopentanoic acid

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About This Item

Linear Formula:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
CAS Number:
74-79-3
Molecular Weight:
174.20
Beilstein:
1725413
EC Number:
200-811-1
MDL number:
MFCD00002635
UNSPSC Code:
12352209
PubChem Substance ID:
329829759
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Product Name

L-Arginine, Vetec™, reagent grade, ≥98%

grade

reagent grade

product line

Vetec™

Assay

≥98%

form

powder

color

white

mp

222 °C (dec.) (lit.)

SMILES string

N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1

InChI key

ODKSFYDXXFIFQN-BYPYZUCNSA-N

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Application


  • L-Arginine-Dependent Nitric Oxide Production in the Blood of Patients with Type 2 Diabetes: A Pilot, Five-Year Prospective Study.: This study examines the role of L-Arginine in nitric oxide production in diabetic patients, proposing its potential benefits for managing vascular complications in diabetes (Stoian et al., 2024).

Biochem/physiol Actions

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

V900343-VAR:
V900343-500G:
V900343-BULK:
V900343-100G:

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF2579V
WXBF4042V
WXBD9997V
WXBF2230V
WXBF1343V

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Ahmed Moursy et al.
Nucleic acids research, 42(10), 6659-6672 (2014-04-03)
Regulation of SMN2 exon 7 splicing is crucial for the production of active SMN protein and the survival of Spinal Muscular Atrophy (SMA) patients. One of the most efficient activators of exon 7 inclusion is hnRNP G, which is recruited
Jia-Yi Dong et al.
American heart journal, 162(6), 959-965 (2011-12-06)
Previous studies suggest that L-arginine, an amino acid and a substrate of nitric oxide synthase, may have blood pressure (BP)-lowering effect. Because some studies were performed with limited number of patients with hypertension and therefore limited statistical power with sometimes
Diane N Singhroy et al.
Retrovirology, 10, 73-73 (2013-07-23)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.
Shiroh Futaki et al.
Current pharmaceutical design, 19(16), 2863-2868 (2012-11-13)
Intracellular delivery using cell-penetrating peptides (CPPs) has received considerable attention as a promising method for introducing exogenous molecules into cells. The mechanisms that enable efficient internalization of CPPs together with cargo molecules are also of interest. In this review, we
Hartmut Grasemann et al.
Current pharmaceutical design, 18(5), 726-736 (2012-01-11)
The concentrations of nitric oxide are decreased in airways of patients with cystic fibrosis. The reasons for this nitric oxide deficiency are incompletely understood but may include reduced production from nitric oxide synthases due to decreased expression, the enzymes in
View All Related Papers

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