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TRUEPEG

Sigma-Aldrich

TrueGel3D Crosslinker

PEG non cell-degradable crosslinker

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

shipped in

dry ice

storage temp.

−20°C

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General description

PEG-Link is comprised of polyethylene glycol and thiol (SH) groups at each end. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran), which results in stable hydrogel. The matrix metalloproteases secreted by cells cannot cleave PEG crosslinker.

Application

TRUEPEG is used to crosslink PVA and dextran polymers to generate stable hydrogel.

Features and Benefits

Non-MMP degradable.

Components

TRUEPEG contains PEG non cell-degradable crosslinker lyophilized and water.

Caution

Avoid prolong exposure of PEG non cell-degradable crosslinker to air.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

Please refer to KIT Component information

PRTR

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FSL

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ISHL Indicated Name

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ISHL Notified Names

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Cartagena Act

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JAN Code

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

True Gel3D™ Hydrogel Troubleshooting

Troubleshoot TrueGel3D™ hydrogel formation and cell viability issues with RGD-degradable polymer and CD cell-degradable crosslinker.

TrueGel3D™ Hydrogel for 3D Cell Culture

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

Protocols

TrueGel3D™ Hydrogel Prep Protocol

TrueGel3D™ hydrogel enables cell encapsulation for 3D culture, mimicking native tissue environment with chemically defined properties.

TrueGel3D™ Hydrogel Prep Protocol

TrueGel3D™ is a chemically defined hydrogel for 3D cell growth, facilitating microchannel filling with slow gelation.

Advanced Protocol: How to Customize your TrueGel3D™ Hydrogel

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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