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Safety Information

T5316

Sigma-Aldrich

TAPS

BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

Synonym(s):

N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H17NO6S
CAS Number:
29915-38-6
Molecular Weight:
243.28
Beilstein:
2452420
EC Number:
249-954-1
MDL number:
MFCD00007538
UNSPSC Code:
12161700
PubChem Substance ID:
24900268

grade

BioPerformance Certified

Assay

≥99.5% (titration)

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

useful pH range

7.7-9.1

pKa 

8.4

mp

230-235 °C (dec.)

solubility

water: 0.5 g/mL, clear, colorless

cation traces

heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, protease, none detected

SMILES string

OCC(CO)(CO)NCCCS(O)(=O)=O

InChI

1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)

InChI key

YNLCVAQJIKOXER-UHFFFAOYSA-N

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

>230.0 °F - closed cup

Flash Point(C)

> 110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T5316-BULK:
T5316-25KG:
T5316-VAR:
T5316-BULK-PC:
T5316-500G:
T5316-25G:
T5316-100G:
T5316-1KG:

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Certificates of Analysis (COA)

Lot/Batch Number
SLCJ7896
SLCB2011
121K5439V
121K5439
110K5421

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Z Zeng et al.
Analytical biochemistry, 252(1), 110-114 (1997-11-05)
High-resolution capillary electrophoresis sizing of preformed complexes of bis-intercalating fluorescent dyes with double-stranded DNA has been demonstrated using hydroxyethylcellulose and 3-[tris-(hydroxymethyl) methylamino]-1-propanesulfonic acid-tetrapentylammonium (Taps-NPe+4) buffers (S. M. Clark and R. A. Mathies, Anal. Chem. 69, 1355-1363, 1997). Such capillary electrophoresis
D Liang et al.
Electrophoresis, 21(17), 3600-3608 (2001-03-29)
A new method to introduce the concentration gradient into the capillary has been developed and its application to DNA capillary electrophoresis is presented. The concentration gradient produced by mixing 5% w/v polyacrylamide-co-poly(N-dimethylacrylamide) (PAM-co-PDMA) solution and 1 x Tris/N-tris(hydroxymethyl)methyl-3-amino-propanesulfonic acid/EDTA (TT)
Seung-ick Oh et al.
TheScientificWorldJournal, 2014, 957548-957548 (2014-07-06)
Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here
Patrick Kwan et al.
Journal of the American Chemical Society, 137(42), 13556-13565 (2015-10-06)
We report the first direct electrochemical characterization of the impact of oxygen on the hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase: hydrogenase I from Pyrococcus furiosus (PfSHI), which grows optimally near 100 °C. Chronoamperometric experiments were used
John-Paul Bacik et al.
The Journal of biological chemistry, 290(44), 26638-26648 (2015-09-12)
The most abundant carbohydrate product of cellulosic biomass pyrolysis is the anhydrosugar levoglucosan (1,6-anhydro-β-d-glucopyranose), which can be converted to glucose 6-phosphate by levoglucosan kinase (LGK). In addition to the canonical kinase phosphotransfer reaction, the conversion requires cleavage of the 1,6-anhydro
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