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T5012

Sigma-Aldrich

Nα-p-Tosyl-L-lysine methyl ester hydrochloride

suitable for ligand binding assays

Synonym(s):

N-(p-Toluenesulfonyl)-L-lysine methyl ester

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About This Item

Empirical Formula (Hill Notation):
C14H22N2O4S · HCl
CAS Number:
5266-48-8
Molecular Weight:
350.86
MDL number:
MFCD00038877
UNSPSC Code:
12352202
PubChem Substance ID:
24900251

product name

Nα-p-Tosyl-L-lysine methyl ester hydrochloride,

form

solid

technique(s)

ligand binding assay: suitable

storage temp.

−20°C

SMILES string

Cl.COC(=O)C(CCCCN)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C14H22N2O4S.ClH/c1-11-6-8-12(9-7-11)21(18,19)16-13(14(17)20-2)5-3-4-10-15;/h6-9,13,16H,3-5,10,15H2,1-2H3;1H

InChI key

NAFMQDMELNDXBJ-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T5012-25MG:
T5012-BULK:
T5012-250MG:
T5012-VAR:
T5012-1G:
T5012-100MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J G van de Winkel et al.
Journal of immunology (Baltimore, Md. : 1950), 145(6), 1890-1896 (1990-09-15)
We have shown previously that certain proteases can modulate the affinity of human Fc gamma RII for IgG. To study whether proteolytic events not only increase FcR affinity, but are essential for Fc gamma R functioning, we evaluated the effect
Tumor cell killing by macrophages activated in vitro with lymphocyte mediators. 5. Role of proteases, inhibitors, and substrates.
W F Piessens et al.
Cellular immunology, 56(2), 286-291 (1980-12-01)
Miri Aharon et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22(8), 847-852 (2002-10-25)
This study investigates the possible involvement of serine proteases in interferon-gamma (IFN-gamma) activity on WISH cells. It was observed that inhibition of (3)H-thymidine incorporation induced by IFN-gamma was abrogated by the serine protease inhibitors Nalpha-tosyl-L-lysyl-chloromethane and soybean trypsin inhibitor, both
T Niwa et al.
Kidney international, 50(4), 1303-1309 (1996-10-01)
Recent work from this laboratory revealed that advanced glycation end product was localized to amyloid deposits in patients with dialysis-related amyloidosis by immunohistochemistry using a monoclonal antibody to advanced glycation end product. To elucidate the epitope of the antibody, N
The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids.
G Kosaki et al.
Thrombosis research, 20(5-6), 587-598 (1980-12-01)

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