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Safety Information

T0388

Sigma-Aldrich

Tartrazine

Dye content ≥85 %, Powder

Synonym(s):

Acid Yellow 23

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About This Item

Empirical Formula (Hill Notation):
C16H9N4Na3O9S2
CAS Number:
Molecular Weight:
534.36
Colour Index Number:
19140
Beilstein:
69850
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.47

product name

Tartrazine, Dye content ≥85 %

form

powder

Quality Level

composition

Dye content, ≥85%

color

orange

solubility

H2O: 10 mg/mL, clear, yellow to orange

density

2.12 at 20 °C

εmax

435-500 at 425-429 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[Na+].[O-]C(=O)C1=NN(c2ccc(cc2)S([O-])(=O)=O)C(=O)C1N=Nc3ccc(cc3)S([O-])(=O)=O

InChI

1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,13H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3

InChI key

UJMBCXLDXJUMFB-UHFFFAOYSA-K

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General description

Tartrazine (Cl 19140) also known as Acid yellow 23, is a hydrophilic polyanionic dye. It is a sulfonic dye, which can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.

Application

Tartrazine may be used as a reference standard in the determination of tartrazine in food samples using ion-pair liquid chromatography coupled with photodiode-array and electrospray mass spectrometry detector.
The application of Tartrazine is seen in the phloxine-tartrazine procedure for cellular inclusions such as viral aggregates and eosinophil granules. It may be used as a substitute for orange G in a variant of Mallory′s trichrome, and in a methyl violet-tartrazine mixture to stain cryptosporidia in faecal smears and mucosal scrapings.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

T0388-BULK:
T0388-100G:
T0388-VAR:
T0388-H:
T0388-500G:


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Daniel C Corbett et al.
Science advances, 6(40) (2020-10-02)
Spatial patterns of gene expression in living organisms orchestrate cell decisions in development, homeostasis, and disease. However, most methods for reconstructing gene patterning in 3D cell culture and artificial tissues are restricted by patterning depth and scale. We introduce a
Stella A Ordoudi et al.
Food chemistry, 267, 410-419 (2018-06-24)
The stepwise approach takes advantage of simple, versatile, low-cost screening tools that can be applied to several posts of the saffron trade chain to specifically detect adulteration with carminic acid (CA). This natural dye is of insect origin and should
Jin Yee Gan et al.
Membranes, 10(8) (2020-08-07)
This study produced a novel polysulfone (PSF) membrane for dye removal using lemon-derived carbon quantum dots-grafted silver nanoparticles (Ag/CQDs) as membrane nanofiller. The preparation of CQDs was completed by undergoing hydrothermal treatment to carbonize the pulp-free lemon juice into CQD
Simultaneous analysis of tartrazine and its intermediates by reversed phase liquid chromatography.
Wittmer PD, et al.
Analytical Chemistry, 47(8), 1422-1423 (1975)
Helen Waechter et al.
Analytical chemistry, 81(21), 9048-9054 (2009-10-10)
Analytical UV absorption detection for microfluidic devices, capillary electrophoresis, and even high-performance liquid chromatography is hampered by the small detection volumes, short absorption paths, and the need to sample at a high rate with a stable background and low noise.

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