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Safety Information

SML3845

Sigma-Aldrich

Enterocin

≥95% (HPLC)

Synonym(s):

(3R,4aR,5S,6S,7S,7aS,8R)-7-Benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one, Vulgamycin

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About This Item

Empirical Formula (Hill Notation):
C22H20O10
CAS Number:
59678-46-5
Molecular Weight:
444.39
UNSPSC Code:
51111800
UNSPSC Code:
12352200
NACRES:
NA.21
Pricing and availability is not currently available.

Quality Level

100

Assay

≥95% (HPLC)

form

(Powder or lyophilized powder)

color

white to off-white

storage temp.

-10 to -25°C

Biochem/physiol Actions

Broad-spectrum antibiotic with activity against both gram-positive and gram-negative bacteria
Enterocin is a bacteriostatic polyketide antibiotic unrelated to the polypeptide enterocin bacteriocins. It has broad-spectrum antibiotic activity against both gram-positive and gram-negative bacteria. Enterocin has also been shown to have inhibitory activity against β-amyloid protein (Aβ1-42) fibrillation and moderate cytotoxicity against HeLa and HepG2 cancer cell lines.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3845-1MG:
SML3845-1MG-PW:
SML3845-BULK:
SML3845-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
0000279471

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Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin
Journal of Natural Products, 78(3), 539-542 (2015)
Exploring Natural Product Artifacts: The Polyketide Enterocin Warms to a Ballet of Isomers
Organic Letters, 22(12), 4828-4832 (2020)
Dong-Bo Xu et al.
Applied microbiology and biotechnology, 99(14), 5825-5832 (2015-04-22)
The type II polyketide synthase (PKS) natural product enterocin (1) was isolated from a mangrove-derived novel species Streptomyces qinglanensis 172205 guided by genome sequence, and its putative biosynthetic gene cluster was revealed. Its natural analogues 5-deoxyenterocin (2) and wailupemycin A-C

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