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SML3614

Sigma-Aldrich

Vatiquinone

≥95% (HPLC)

Synonym(s):

α-tocotrienol quinone, 2-[(3R,6E,10E)-3-Hydroxy-3,7,11,15-tetramethyl-6,10,14-hexadecatrien-1-yl]-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione, ATQ3, EPI 743, EPI-743

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About This Item

Empirical Formula (Hill Notation):
C29H44O3
CAS Number:
1213269-98-7
Molecular Weight:
440.66
MDL number:
MFCD28963977
UNSPSC Code:
12352200
NACRES:
NA.21
Pricing and availability is not currently available.

Quality Level

100

Assay

≥95% (HPLC)

form

oil

color

, Colorless to light yellow

storage temp.

-10 to -25°C

Related Categories

Biochem/physiol Actions

Orally available, highly potent analog of coenzyme Q10 that modulates the activity of oxidoreductases and improves cell redox status
Vatiquinone (EPI-743), a metabolite of a-tocotrienol, is an orally available and highly potent analog of coenzyme Q10 that modulates the activity of oxidoreductases including AD(P)H:quinone oxidoreductase 1, resulting in increased cellular GSH concentration and improvement in redox status. Vatiquinone is an agent designated to treat mitochondrial diseases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3614-VAR:
SML3614-BULK:
SML3614-5MG:
SML3614-25MG:

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Rapid identification of a novel complex I MT-ND3 m.10134C>A mutation in a Leigh syndrome patient
PLoS ONE, 9(8), e10487-e10487 (2014)
S Küpeli et al.
The Journal of urology, 141(2), 378-378 (1989-02-01)
We describe a patient with a radiopaque calculus in the vas deferens that was inappropriately diagnosed as a ureteral calculus.
William D Shrader et al.
Bioorganic & medicinal chemistry letters, 21(12), 3693-3698 (2011-05-24)
We report that α-tocotrienol quinone (ATQ3) is a metabolite of α-tocotrienol, and that ATQ3 is a potent cellular protectant against oxidative stress and aging. ATQ3 is orally bioavailable, crosses the blood-brain barrier, and has demonstrated clinical response in inherited mitochondrial

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