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Safety Information

SML3277

Sigma-Aldrich

HDL mimetic peptide 4F trifluoroacetate

≥95% (HPLC)

Synonym(s):

Ac-DWFKAFYDKVAEKFKEAF-NH2 trifluoroacetate, L-4F trifluoroacetate, N-Acetyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-lysyl-L-alanyl-L-phenylalanyl-L-tyrosyl-L-α-aspartyl-L-lysyl-L-valyl-L-alanyl-L-α-glutamyl-L-lysyl-L-phenylalanyl-L-lysyl-L-α-glutamyl-L-alanyl-L-phenylalaninamide trifluoroacetate

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1 MG
¥10,600

¥10,600

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1 MG
¥10,600

About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

¥10,600

Check Cart for Availability
Request a Bulk Order

Quality Level

100

Assay

≥95% (HPLC)

form

powder

color

white to beige

storage temp.

−20°C

Biochem/physiol Actions

Brain blood barrier penetrant small amphipathic peptide that exhibits anti-inflammatory, antioxidant and anti-atherogenic properties in animal models.
HDL mimetic peptide 4F is a brain blood barrier penetrant small amphipathic peptide that exhibits anti-inflammatory, antioxidant and anti-atherogenic properties in animal models. HDL mimetic peptide 4F increases the brain efflux of intracerebrally injected 125I-Aβ42. It suppresses proinflammatory monocytes and macrophages and alleviates post myocardial infarction remodeling in a mouse model.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3277-VAR:
SML3277-BULK:
SML3277-1MG-PW:
SML3277-1MG:

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Certificates of Analysis (COA)

Lot/Batch Number
0000166315
0000166315

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Daniela Busse et al.
The Journal of investigative dermatology, 134(11), 2823-2832 (2014-07-08)
As the outermost barrier of the body, the skin is exposed to multiple environmental factors, including temperature, humidity, mechanical stress, and chemical stimuli such as odorants that are often used in cosmetic articles. Keratinocytes, the major cell type of the
S Manteniotis et al.
Cell death discovery, 2, 15070-15070 (2016-08-24)
The olfactory receptor (OR) family was found to be expressed mainly in the nasal epithelium. In the last two decades members of the OR family were detected to be functional expressed in different parts of the human body such as
Barbara Pavan et al.
Drug discovery today, 22(7), 1123-1130 (2017-05-24)
Several olfactory receptors (ORs) have been characterized outside the olfactory neuroepithelium in neuronal and non-neuronal tissues, where they were implicated in the recognition of diverse chemical signals. ORs have been found to regulate melanogenesis in skin melanocytes, and OR expression
Jérémy Chéret et al.
Nature communications, 9(1), 3624-3624 (2018-09-20)
Olfactory receptors are expressed by different cell types throughout the body and regulate physiological cell functions beyond olfaction. In particular, the olfactory receptor OR2AT4 has been shown to stimulate keratinocyte proliferation in the skin. Here, we show that the epithelium

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