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SML3208

Sigma-Aldrich

CPYPP

≥98% (HPLC)

Synonym(s):

4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione

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5 MG
¥14,700
25 MG
¥58,700

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5 MG
¥14,700
25 MG
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About This Item

Empirical Formula (Hill Notation):
C18H13ClN2O2
CAS Number:
310460-39-0
Molecular Weight:
324.76
MDL number:
MFCD00980987
UNSPSC Code:
51111800
NACRES:
NA.77

¥14,700

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

orange to dark red

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3

InChI

1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)

InChI key

VVZJFICTTKPNCK-UHFFFAOYSA-N

Biochem/physiol Actions

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain

Storage Class Code

11 - Combustible Solids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML3208-BULK:
SML3208-25MG:
SML3208-VAR:
SML3208-5MG:

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