Skip to Content
Merck
All Photos(1)

Documents

Safety Information

SML2712

Sigma-Aldrich

ES9-17

≥98% (HPLC)

Synonym(s):

5-Bromo-2-thiophenesulfonanilide, 5-Bromo-N-phenyl-2-thiophenesulfonamide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H8BrNO2S2
CAS Number:
55854-43-8
Molecular Weight:
318.21
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=S(NC1=CC=CC=C1)(C2=CC=C(S2)Br)=O

Biochem/physiol Actions

ES9-17 is a potent and selective inhibitor of clathrin-mediated endocytosis (CME) that binds to N-terminal domain of clathrin heavy chain. ES9-17 inhibits uptake of different endocytic cargoes in Arabidopsis and HeLa cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML2712-25MG:
SML2712-5MG:
SML2712-VAR:
SML2712-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Wim Dejonghe et al.
Nature chemical biology, 15(6), 641-649 (2019-04-24)
Clathrin-mediated endocytosis (CME) is a highly conserved and essential cellular process in eukaryotic cells, but its dynamic and vital nature makes it challenging to study using classical genetics tools. In contrast, although small molecules can acutely and reversibly perturb CME

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service