Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

Safety Information

SML2398

Sigma-Aldrich

SR16832

≥98% (HPLC)

Synonym(s):

2-Chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide

Sign Into View Organizational & Contract Pricing

Select a Size

5 MG
¥13,770
25 MG
¥44,630

¥13,770

Estimated to ship onApril 12, 2025

Request a Bulk Order
All Photos(1)

Select a Size

Change View
5 MG
¥13,770
25 MG
¥44,630

About This Item

Empirical Formula (Hill Notation):
C17H12ClN3O4
CAS Number:
2088135-12-8
Molecular Weight:
357.75
UNSPSC Code:
12352200
NACRES:
NA.77

¥13,770

Estimated to ship onApril 12, 2025

Request a Bulk Order

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=C(C=C(OC)C=C3)C3=NC=C2)=O

InChI

1S/C17H12ClN3O4/c1-25-11-3-5-15-13(9-11)16(6-7-19-15)20-17(22)12-8-10(21(23)24)2-4-14(12)18/h2-9H,1H3,(H,19,20,22)

InChI key

CVTZAGCRUDYUGB-UHFFFAOYSA-N

Biochem/physiol Actions

PPARγ antagonist
SR16832 is a PPARγ antagonist. It acts as a dual-site covalent inhibitor of PPARγ inhibiting both orthosteric and allosteric cellular activation by the PPARγ agonists.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML2398-VAR:
SML2398-25MG:
SML2398-BULK:
SML2398-5MG:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Richard Brust et al.
ACS chemical biology, 12(4), 969-978 (2017-02-07)
GW9662 and T0070907 are widely used commercially available irreversible antagonists of peroxisome proliferator-activated receptor gamma (PPARγ). These antagonists covalently modify Cys285 located in an orthosteric ligand-binding pocket embedded in the PPARγ ligand-binding domain and are used to block binding of

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service