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SML2058

Sigma-Aldrich

5,7-Dihydroxytryptamine hydrobromide

≥94% (HPLC)

Synonym(s):

3-(2-Aminoethyl)-1H-indole-5,7-diol, 5,7-DHT hydrobromide, 5,7-DiHT hydrobromide, 7-Hydroxyserotonin hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C10H12N2O2 · xHBr
CAS Number:
31363-74-3
Molecular Weight:
192.21 (free base basis)
MDL number:
MFCD08690516
UNSPSC Code:
12352116
NACRES:
NA.77

Assay

≥94% (HPLC)

form

powder

storage condition

desiccated

color

white to dark brown

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NCCC1=CNC2=C(O)C=C(O)C=C21.[H]Br

InChI

1S/C10H12N2O2/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14/h3-5,12-14H,1-2,11H2

InChI key

LXWHQTNFZDTKBH-UHFFFAOYSA-N

Biochem/physiol Actions

5,7-Dihydroxytryptamine is a neurotoxin that selectively kills serotonergic neurons.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML2058-VAR:
SML2058-5MG:
SML2058-25MG:
SML2058-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rani K Vasudeva et al.
Behavioural brain research, 295, 35-44 (2015-06-16)
Alcoholism afflicts 1 in 13 US adults, and comorbidity with depression is common. Levels of serotonin (5-HT) metabolites in alcoholic or depressed humans and rat strains are lower compared to healthy counterparts. Rats bred for ethanol (EtOH) preference are common
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Pharmacological reports : PR, 65(4), 771-786 (2013-10-23)
This review contains background information on the serotonin system, furthermore the suggestion to introduce the term Contemporary Witness Report (CWR) for a novel type of review and, as the main part, an overview over the history of serotonin discovery as

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