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Safety Information

SML2027

Sigma-Aldrich

L-2-oxothiazolidine-4-carboxylic acid propargyl amide

≥98% (HPLC)

Synonym(s):

(R)-2-Oxo-N-2-propyn-1-yl-4-thiazolidinecarboxamide, OTC propargyl amide, OTC-PA

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About This Item

Empirical Formula (Hill Notation):
C7H8N2O2S
CAS Number:
2165706-30-7
Molecular Weight:
184.22
MDL number:
MFCD30729654
UNSPSC Code:
12352106
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

C#CCNC([C@@H]1CSC(N1)=O)=O

Biochem/physiol Actions

L-2-oxothiazolidine-4-carboxylic acid propargyl amide is a cell penetrant, potent and selective competitive inhibitor of cystathionine-γ-lyase that completely abrogated L-cysteine-induced vasorelaxation in tissue.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML2027-VAR:
SML2027-25MG:
SML2027-5MG:
SML2027-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Angela Corvino et al.
Scientific reports, 6, 34398-34398 (2016-10-07)
Hydrogen sulfide is an essential catabolite that intervenes in the pathophysiology of several diseases from hypertension to stroke, diabetes and pancreatitis. It is endogenously synthesized mainly by two pyridoxal-5'-phosphate-dependent enzymes involved in L-cysteine metabolism: cystathionine-ß-synthase (CBS) and cystathionine-γ-lyase (CSE). Research

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