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Safety Information

SML1623

Sigma-Aldrich

MSP-3

≥98% (HPLC)

Synonym(s):

N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide

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About This Item

Empirical Formula (Hill Notation):
C16H19NO3S
CAS Number:
1820968-63-5
Molecular Weight:
305.39
UNSPSC Code:
12352200
PubChem Substance ID:
329825508
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

oil

color

white to beige

storage temp.

room temp

SMILES string

O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2

InChI

1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)

InChI key

HCUVEUVIUAJXRB-UHFFFAOYSA-N

Biochem/physiol Actions

MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1623-25MG:
SML1623-BULK:
SML1623-5MG:
SML1623-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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