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Safety Information

SML1475

Sigma-Aldrich

Ampiroxicam

≥98% (HPLC)

Synonym(s):

CP 65703, Carbonic acid ethyl 1 -[[2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester, Carbonic acid ethyl 1-[[2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl]oxy]ethyl ester S,S-dioxide

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¥12,500

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Estimated to ship onApril 24, 2025

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5 MG
¥12,500

About This Item

Empirical Formula (Hill Notation):
C20H21N3O7S
CAS Number:
99464-64-9
Molecular Weight:
447.46
MDL number:
MFCD00866079
UNSPSC Code:
12352200
PubChem Substance ID:
329825906
NACRES:
NA.77

¥12,500

Estimated to ship onApril 24, 2025

New, lower price on this item!
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Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CCOC(OC(OC1=C(C(NC2=CC=CC=N2)=O)N(C)S(=O)(C3=CC=CC=C31)=O)C)=O

InChI

1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)

InChI key

LSNWBKACGXCGAJ-UHFFFAOYSA-N

Biochem/physiol Actions

Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID), a prodrug of Cox 1/2 inhibitor piroxicam.
Ampiroxicam is an ether carbonate prodrug.This nonacidic drug does not have the ability to prevent detectable prostaglandin production in vitro.[1]
Antiinflammatory NSAID, prodrug of piroxicam

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1475-VAR:
SML1475-25MG:
SML1475-BULK:
SML1475-5MG:

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Certificates of Analysis (COA)

Lot/Batch Number
105M4758V

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T J Carty et al.
Agents and actions, 39(3-4), 157-165 (1993-07-01)
Ampiroxicam is a nonacidic ether carbonate prodrug of piroxicam. Our results demonstrate that, in contrast to piroxicam, ampiroxicam does not possess detectable prostaglandin synthesis inhibitory activity in vitro. Ampiroxicam, however, has similar in vivo potency to piroxicam in suppressing paw

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