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Key Documents

Safety Information

SML1140

Sigma-Aldrich

ML138

≥98% (HPLC)

Synonym(s):

2-[5-[[(3,4-Dichlorophenyl)methyl]thio]-4-(2-furanylmethyl)-4H-1,2,4-triazol-3-yl]-pyridine, CID 44601470, CID44601470, ML-138

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About This Item

Empirical Formula (Hill Notation):
C19H14Cl2N4OS
CAS Number:
Molecular Weight:
417.31
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

ClC1=CC(CSC2=NN=C(C3=NC=CC=C3)N2CC4=CC=CO4)=CC=C1Cl

InChI

1S/C19H14Cl2N4OS/c20-15-7-6-13(10-16(15)21)12-27-19-24-23-18(17-5-1-2-8-22-17)25(19)11-14-4-3-9-26-14/h1-10H,11-12H2

InChI key

QDXGAJIGONMOCL-UHFFFAOYSA-N

Biochem/physiol Actions

ML138 (CID 44601470) is a highly selective agonist at kappa opioid receptors (KOR) that potently activate G protein coupling but weakly interact with β arrestin2.
ML138 is a highly selective agonist at kappa opioid receptors (KOR).

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1140-25MG:
SML1140-BULK:
SML1140-VAR:
SML1140-5MG:


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