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Safety Information

SML1011

Sigma-Aldrich

INDY

≥98% (HPLC)

Synonym(s):

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone

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5 MG
¥17,800
25 MG
¥57,900

¥17,800

Estimated to ship onMay 31, 2025

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5 MG
¥17,800
25 MG
¥57,900

About This Item

Empirical Formula (Hill Notation):
C12H13NO2S
CAS Number:
1169755-45-6
Molecular Weight:
235.30
UNSPSC Code:
12352200
NACRES:
NA.77

¥17,800

Estimated to ship onMay 31, 2025

Request a Bulk Order

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

S1c2c(cc(cc2)O)N(\C\1=C/C(=O)C)CC

InChI

1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3/b12-6+

InChI key

GCSZJMUFYOAHFY-WUXMJOGZSA-N

Biochem/physiol Actions

INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.
INDY is a potent inhibitor of Dyrk1A and Dyrk1B.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML1011-25MG:
SML1011-BULK:
SML1011-5MG:
SML1011-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
044M4741V

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