Skip to Content
Merck
All Photos(1)

Key Documents

Safety Information

SML0818

Sigma-Aldrich

A-841720

≥98% (HPLC)

Synonym(s):

9-(Dimethylamino)-3-(hexahydro-1H-azepin-1-yl)-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-one

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H21N5OS
CAS Number:
869802-58-4
Molecular Weight:
343.45
UNSPSC Code:
12352202
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

SMILES string

[s]1c2nccc(c2c3nc[n]([c](c31)=O)N4CCCCCC4)N(C)C

InChI

1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3

InChI key

GYWGXEGOXODOQU-UHFFFAOYSA-N

Biochem/physiol Actions

A-841720 is a potent, selective, non-competitive mGluR1 antagonist that displays greater than 30-fold selectivity over another Group I metabotopic glutamate receptor, mGluR5. The compound has potent analgesic properties, and can also diminish motor and cognitive activity.
A-841720 is a potent, selective, non-competitive mGluR1 antagonist.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML0818-BULK:
SML0818-25MG:
SML0818-VAR:
SML0818-5MG:

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000029404
093M4618V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Glutamate Receptors (G Protein Family)

Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service