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Key Documents

Safety Information

SML0813

Sigma-Aldrich

BRD56491

≥98% (HPLC)

Synonym(s):

2-(4-Methylphenyl)-4H-benzo[h]chromen-4-one, 2-(4-Methylphenyl)-4H-naphtho[1,2-b]pyran-4-one

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5 MG
¥16,920
25 MG
¥68,950

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5 MG
¥16,920
25 MG
¥68,950

About This Item

Empirical Formula (Hill Notation):
C20H14O2
CAS Number:
14756-26-4
Molecular Weight:
286.32
UNSPSC Code:
12352200
NACRES:
NA.77

¥16,920

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death.
BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death. However, combining BRD56491 with nontoxic doses of the glutathione synthesis inhibitor L-buthionine sulfoximine did lead to cell death in a variety of cancer cell lines. BRD56491 can be used to create a more oxidizing cell state and aid in studies of cancer cell lines resilient to induced increases in ROS levels.

Hazard Statements

H413

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML0813-25MG:
SML0813-5MG:
SML0813-BULK:
SML0813-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
083M4627V

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