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Key Documents

Safety Information

SML0226

Sigma-Aldrich

Pseudocantharidin C

≥98% (HPLC)

Synonym(s):

(4-Bromophenyl) ((3aR,4R,7S,7aS)-rel-4,7-Epoxy-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)methanone

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About This Item

Empirical Formula (Hill Notation):
C15H16BrNO2
CAS Number:
1301756-81-9
Molecular Weight:
322.20
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥15 mg/mL

storage temp.

2-8°C

Biochem/physiol Actions

Pseudocantharidin C is an activator of PP2A
Pseudocantharidin C stimulates PP2A activity up to two-fold without influencing PP1. PP2A activation by pseudocantharidin C changes phosphorylation of tra2-beta1 at position T33 and promotes the SMN2 pre-mRNA exon 7 inclusion.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Serine/Threonine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SML0226-VAR:
SML0226-5MG:
SML0226-25MG:
SML0226-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
012M4609V

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