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Merck
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Key Documents

Safety Information

SHH0022

Sigma-Aldrich

Histoheme

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About This Item

UNSPSC Code:
12171500

application(s)

hematology
histology

storage temp.

room temp

General description

Developed to assist histologists with bloody specimens such as placental fragments, bone marrow biopsies, liver, spleen and endometrial curettings which tend to harden after processing and dry out. When set on ice, these tissues are prone to shatter and flake, leaving blood fragments on the work area, microtome, and water bath, and have a high potential to create extraneous tissue “floaters” on slides.

Histoheme is an ammonia based emollient that alleviates these problems and mess. Trimming into these blocks and soaking tissue in Histoheme allows technicians to cut clean, non-fragmented sections without stopping in-between each block to allow for better morphological staining.

Testing Method

Procedure
1. Trim blocks 10-20 microns.
2. Soak in small amounts of Histoheme. After use, dispose of used Histoheme to prevent cross-contamination with other samples.
3. Place block in microtome chuck and recut for 4-5 μm sections.

Histoheme does not have any effect on H&E staining or immunohistochemistry stains. The product is completely removed during the deparaffinization process.

Signal Word

Danger

Hazard Statements

H314,H335,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

ISHL Indicated Name

Substances Subject to be Indicated Names

ISHL Notified Names

Substances Subject to be Notified Names

JAN Code

SHH0022-250ML-PW:
SHH0022-250ML:4548174009352
SHH0022-BULK:
SHH0022-VAR:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ0259

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