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Key Documents

Safety Information

SAE0219

Sigma-Aldrich

Mucin Degradation Enzyme

for preparative digestions, powder

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About This Item

Quality Level

200

form

powder

shelf life

2 yr (retest)

storage condition

protect from light

shipped in

dry ice

storage temp.

-10 to -25°C

General description

Mucin Degradation Enzyme is a metalloprotease useful for digesting heavily O-glycosylated mucin proteins. This product is made for preparative scale digestions of viscous material that is dense with mucin-type glycoproteins.

Application

For use as a sample preparation tool in research and discovery. Used for proteolytic degradation of mucin-dense tissues to allow for downstream processing.

Biochem/physiol Actions

The Mucin Degradation enzyme is a mutated form of a protease that specifically recognizes densely glycosylated mucins and mucin-domains, and proteolytically cleaves the peptide backbone. In nature this presumably enhances the virulence of the pathogenic microbe, but in the laboratory is a useful way of accessing molecular structures in tissues normally shielded by mucins.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAE0219-5MG:
SAE0219-BULK:
SAE0219-VAR:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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