SAE0160

Albumin human

Exbumin^™, Recombinant, lyophilized powder, Animal Component Free, suitable for cell culture, low endotoxin

• Synonym(s): ExbuminInVitria, rHSA
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• biological source: human
• Quality Level: 100
• form: powder
• mol wt: monomer ~67 kDa
• concentration: >96%
• technique(s): cell culture | mammalian: suitable
• impurities: Endotoxin, tested
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

Exbumin^™ is high-purity recombinant human serum albumin with high lysine reactivity. It contains low levels of albumin aggregates and lipids and high concentration of free-thiol/Cys-34 mercapto-albumin. This USA-origin rHSA is animal-free.

Application

ExbuminInvitria is recombinant human serum that acts as carrier protein for fatty acids and growth factors. It is added as an ingredient to classical and custom media formulations. This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells. ExbuminInvitria has been observed to improve the performance of multiple cell types.

Biochem/physiol Actions

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. They are also vital in regulating the colloidal osmotic pressures of blood. Serum albumins protect the cells against physical or toxins-induced stress.

Features and Benefits

Exbumin^™ is animal component free that is manufactured using good manufacturing practices at an ISO9001:2015 certified facility. Exbumin is also used to maintain tissue viability during cryo-preservation or storage.
Advantages

• Eliminates animal-derived additives
• Safe and regulatory friendly
• Provides well-defined and consistent stem cell medium
• Raw materials, manufacturing equipment, and packaging is certified blood free and animal free

Packaging

5 g in poly bottle

Preparation Note

To prepare stock solutions, gently dissolve Exbumin in DPBS, PBS or basal media at a concentration of 50-100mg/mL. If needed, allow Exbumin to completely dissolve overnight at 4°C in a dark environment. Filter sterilization with a 0.8μm filter followed by a 0.2μm filter is recommended. Liquid solutions can be stored for 4 weeks at 4°C in the dark.

Other Notes

Exbumin is a trademark of InVitria

Legal Information

rHSA manufactured in the USA by InVitria US Pat 10618951, 10981974, and 11492389.

Exbumin is a trademark of Ventria Bioscience Inc.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable