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Safety Information

SAB5700433

Sigma-Aldrich

Anti-Phospho-PDGFRA-Y1018 antibody produced in rabbit

Synonym(s):

CD140A, GAS9, PDGFR-2, PDGFR2, PDGFRA, RHEPDGFRA

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

122
 24
 82

species reactivity

human

concentration

3.56 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

P16234

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr1018)

Gene Information

human ... PDGFRA(5156)

General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Immunogen

A synthetic phosphorylated peptide around Y1018 of human PDGFRA (NP_006197.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB5700433-100UL:

Certificates of Analysis (COA)

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