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Safety Information

SAB5700386

Sigma-Aldrich

Anti-Phospho-AURKA-T288 antibody produced in rabbit

Synonym(s):

AIK, ARK1, AURA, AURKA, BTAK, PPP1R47, STK15, STK6, STK7

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

45

species reactivity

human

concentration

3.55 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

O14965

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr288)

Gene Information

human ... AURKA(6790)

General description

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around T288 of human AURKA (NP_003591.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

SAB5700386-100UL:

Certificates of Analysis (COA)

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