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Key Documents

SAB4501843

Sigma-Aldrich

Anti-MCL1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Bcl-2-related protein EAT/mcl1, EAT/MCL-1, induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, myeloid cell leukemia sequence 1

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100 μG
¥68,600

¥68,600

Estimated to ship onApril 21, 2025

New, lower price on this item!
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100 μG
¥68,600

About This Item

MDL number:
MFCD01324498
UNSPSC Code:
12352203
NACRES:
NA.41

¥68,600

Estimated to ship onApril 21, 2025

New, lower price on this item!

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 37 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000
western blot: 1:500-1:1000

NCBI accession no.

Q07820

UniProt accession no.

Q07820

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MCL1(4170)

General description

Anti-MCL1 Antibody detects endogenous levels of total MCL1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human MCL1.

Immunogen Range: 125-174

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
211097

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Andrea Štefaniková et al.
General physiology and biophysics, 36(5), 539-547 (2018-01-27)
Colorectal carcinoma (CRC) that represents one of the major causes for cancer-related death in humans is often associated with over-expression of anti-apoptotic proteins of Bcl-2 family. The aim of presented study was to determine the effect of ABT-737 inhibitor of
María A Rodríguez-Hernández et al.
Journal of cellular physiology, 234(1), 692-708 (2018-08-23)
Sorafenib is the unique accepted molecular targeted drug for the treatment of patients in advanced stage of hepatocellular carcinoma. The current study evaluated cell signaling regulation of endoplasmic reticulum (ER) stress, c-Jun-N-terminal kinase (JNK), Akt, and 5'AMP-activated protein kinase (AMPK)
Yunjie Zhang et al.
Oncology letters, 15(4), 5620-5626 (2018-03-20)
The present study assessed the mechanism underlying the effect of sorafenib on the proliferation and apoptosis of the acute promyelocytic leukemia (APL) cell line NB4. NB4 cells were treated with different concentrations of sorafenib (0, 1.5, 3, 6, and 12

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